薛志远,徐 平.转化生长因子-β1与认知障碍的相关性研究进展[J].转化医学杂志,2019,8(3):186-188
转化生长因子-β1与认知障碍的相关性研究进展
Advances research on the relationship between transforming growth factor-β1 and cognitive dysfunction
  
DOI:
中文关键词:  认知障碍  转化生长因子-β1  神经递质  肠道菌群  脂联素
英文关键词:Cognitive dysfunction  Tansforming growth factor beta 1 (TGF-β1)  Neurotransmitters  Gut microbial  Adiponectin
基金项目:
作者单位
薛志远 遵义医科大学附属医院神经内科 
徐 平 遵义医科大学附属医院神经内科 
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中文摘要:
      认知障碍指与学习、记忆、语言、思维、情感等有关的大脑高级智能加工过程出现异常,导致注意障碍、记忆障碍、执行障碍等,已经成为严重的社会公共健康问题,但目前仍缺乏安全有效疗法。转化生长因子β1(tansforming growth factor beta 1,TGF-β1)是TGF-β家族中的最重要成员之一,可通过多种途径改善认知功能,为认知障碍的治疗提供新的策略。作者对TGF-β1在认知障碍中的作用研究进展进行综述。
英文摘要:
      Cognitive dysfunction refers to abnormalities in the brain’s advanced intelligent processing processes related to learning, memory, language, thinking and emotion, which leaded to attention, memory and executive dysfunction. It has become a serious social public health problem, but it still lacks of safe and effective therapy. Tansforming growth factor beta 1 (TGF-β1) is one of the most important members of the TGF-β family, which can improve cognitive function through various ways and provide new strategies for the treatment of cognitive dysfunction. This paper reviews the research progress of the role of TGF-β1 in cognitive dysfunction
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