范立凤.咽喉感觉异常患者的镜下诊断与病理学分析[J].转化医学杂志,2021,10(4):234-238
咽喉感觉异常患者的镜下诊断与病理学分析
The croscopic diagnosis and pathological analysis of patients with dysphonia of pharynx and larynx
  
DOI:
中文关键词:  电子喉镜  声带白斑  喉部肿瘤  活检  病理学分析
英文关键词:Electronic laryngoscope  Vocal cord white spot  Laryngeal tumor  Biopsy  Pathological analysis
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作者单位
范立凤 十堰市中医医院脾胃肺病科 
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中文摘要:
      目的 探讨电子喉镜对因咽喉部肿物引起咽喉感觉异常患者的临床诊断和应用,并对病理结果进行分析。方法 随机选择2019年10月-2020年4月因咽喉部肿物引起的咽喉感觉异常患者共200例,年龄18~65岁。其中声带白斑患者68例、喉部肿瘤患者98例及下咽部肿瘤患者34例。200例患者均于门诊电子喉镜下表面麻醉,随后对其进行组织活检以及病理检查。分析以上三类患者的性别与年龄分布,并对其进行病理学分析。结果 三类疾病的高发年龄段均为61~70岁;声带白斑患者中,可疑浸润癌患者有2例,占比2.9%;浸润癌患者有1例,占比1.5%;喉部肿瘤患者中,可疑浸润癌患者有15例,占比15.3%;浸润癌患者有47例,占比48%;下咽部肿瘤患者中,可疑浸润癌患者有5例,占比14.7%;浸润癌患者有24例,占比70.6%;三类病变男性患者占97.5%,女性患者仅占2.5%;97%的人有抽烟和酗酒的习惯,对三类病变进行接受者操作特性曲线(receiver operating characteristic curve,ROC)分析,抽烟+酗酒的ROC评分为0.802。结论 电子喉镜的操作方式便捷,能够有效、快捷地完成活检,获取患者的具体病情,为后续治疗提供依据。
英文摘要:
      Objective To explore the application of electronic laryngoscope in clinical diagnosis of patients with abnormal sensation of throat caused by throat tumor. Methods During October 2019 and April 2020, 200 patients aged from 18 to 65 with pharyngeal paresthesia caused by pharyngeal masses were randomly selected for analysis. There were 68 cases of vocal cord leukoplakia, 98 cases of laryngeal tumor, and 34 cases of hypopharyngeal tumor. All the 200 patients were anesthetized under the electronic laryngoscope, and then underwent tissue biopsy and pathological examination. The gender distribution and age distribution of the above three types of patients were analyzed, and the pathological analysis was carried out. The results were used to evaluate the clinical diagnostic value and significance of electronic laryngoscope in patients with laryngeal paresthesia. Result The high incidence age of three kinds of diseases were 61-70 years old. Among patients with vocal cord leukoplakia, 2 cases were suspected of invasive cancer, accounting for 2.9%, 1 case was suspected of invasive cancer, accounting for 1.5%. Among patients with laryngeal tumor, 15 cases were suspected of invasive cancer, accounting for 15.3%, 47 cases were suspected of invasive cancer, accounting for 48%. Among patients with hypopharyngeal tumor, 5 cases were suspected of invasive cancer, accounting for 14.7%. Among patients with invasive cancer, 5 cases were suspected of invasive cancer, accounting for 14.7%, 24 cases were invasive cancer, accounting for 70.6%. In the 200 patients, male patients accounted for 97.5%, while female patients only accounted for 2.5%. 97% of the people had the habit of smoking and drinking. and the ROC score of smoking + drinking was 0.802. Conclusion The operation mode of electronic laryngoscope is convenient, which can effectively and quickly complete the biopsy, obtain the specific condition of patients, and provide the basis for the follow-up treatment.
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