倪 荣,顾顺忠,陆 洋,刘志云.不同部位起搏对缓慢性心律失常患者的疗效及对其LV相关指标和CQQC评分的影响初步评估[J].转化医学杂志,2022,11(5):306-308
不同部位起搏对缓慢性心律失常患者的疗效及对其LV相关指标和CQQC评分的影响初步评估
Preliminary evaluation of the efficacy of different sites of pacing in patients with bradyarrhythmias and the effect on their left ventricular related indicators and other indicators and CQQC scores
  
DOI:
中文关键词:  缓慢性心律失常  起搏点部位;心室机械收缩同步性指标;疗效
英文关键词:Bradyarrhythmias  Pacing sites  Ventricular mechanical contraction synchrony index  Efficacy
基金项目:
作者单位
倪 荣 江苏省海安市人民医院心血管内科 
顾顺忠 江苏省海安市人民医院心血管内科 
陆 洋 江苏省海安市人民医院心血管内科 
刘志云 江苏省海安市人民医院心血管内科 
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中文摘要:
      目的 探讨不同部位放置起搏器对缓慢性心律失常患者的疗效及对其左心室(left ventricular,LV)功能和患者生活质量的影响。方法 选取2020年1月-2021年12月海安市人民医院收治的83例缓慢性心律失常的患者,根据永久性起搏器植入的部位分为两组。其中研究组患者43例,采用右心室间隔植入心脏永久性起搏器治疗;对照组患者40例,则采用右心室心尖部植入心脏永久性起搏器治疗,比较两组患者的心功能情况、临床疗效、生活质量等差异。结果 植入术后研究组的左心室射血分数(left ventricular ejection fraction,LVEF)高于对照组,左心室舒张末期内径(left ventricular end diastolic dimension,LVEDD)和左心室收缩末期内径(left ventricular end-systolic dimension, LVESD)均低于对照组(P<0.05)。植入术后研究组的心室机械收缩同步性指标及心肌受损相关指标低于对照组(P<0.05)。植入术后两组的心脏不良事件发生率比较无差异(P>0.05)。植入术后两组的生活质量均较术前升高,且研究组更高(P<0.05)。结论 右心室间隔起搏可更为显著的改善缓慢性心律失常患者的心功能情况,同时不增加术后的并发症发生率,最终改善患者的生活质量。
英文摘要:
      Objective To investigate the efficacy of different sites of pacemaker in patients with bradyarrhythmias and their effects on the function of left ventricular(LV) and quality of life. Methods Eighty-three patients with slow-onset arrhythmias admitted to our hospital from January 2020 to December 2021 were selected and divided into 2 groups according to the implantation sites of permanent pacemaker. The permanent cardiac pacemakers were implanted in the right ventricular septum in forty-three patients of the study group while it was right ventricular apical region in 40 patients in the control group were treated with permanent cardiac pacemakers implanted of the right ventricular apical region. The differences in clinical efficacy between the two groups were compared. Results After implantation, left ventricular ejection fraction (LVEF) in study group was higher than that in the control group, while left ventricular end diastolic dimension (LVEDD) and left ventricular end systolic dimension (LVESD) were lower than these in the control group (P<0.05). Ventricular mechanical systolic synchrony index and myocardial damage related index in study group were lower than these in the control group after implantation (P<0.05). there was no difference in the incidence rate of adverse cardiac events between the the two groups after implantation (P>0.05). the quality of life in both groups after implantation was higher than that before operation, and the study group was higher (P<0.05). Conclusion Right ventricular septal pacing can improve cardiac function more significantly in patients with bradyarrhythmias without increasing the incidence of postoperative complications, ultimately improving the quality of life of patients, and is worthy of clinical application.
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